BMJ  2007;335 (7 July), doi:10.1136/bmj.39267.396667.43

Editor's Choice

US editor's choice

New types of Paps and puffs

The first 150 words of the full text of this article appear below.

In the US liquid-based cytology for cervical screening has replaced conventional cytology in many settings. Although there has been a lot of research on the liquid-based technology, few randomized trials have appeared. Two studies, an editorial, and a commentary in this issue add to the confidence that a move to liquid-based techniques is of both clinical and programmatic benefit.

Guglielmo Ronco and colleagues randomized over 45 000 women to receive either conventional or liquid based cytology (doi: 10.1136/bmj.39196.740995.BE). They found that the liquid technique clearly reduced the number of unsatisfactory smears with no decrease in sensitivity, although the number of false positives was increased. Liquid cytology also allows for human papillomavirus testing, which conventional smears do not.

In a prospective analysis of over 55 000 split sample pairs, Elizabeth Davey and associates found an increased sensitivity with the automated reading that is possible with liquid-based cytology compared with conventional . . . [Full text of this article]

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