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BMJ 2007;334:1240 (16 June), doi:10.1136/bmj.39244.725810.DB
Susan Mayor
London
| The first 150 words of the full text of this article appear below. |
Women who undergo breast conserving surgery for early breast cancer should be followed up for much longer than the three to five years recommended in current guidelines, warns a study published this week. The study shows that relapses can occur at least 10 years after initial treatment.
The study, published in the British Journal of Cancer, analysed relapses in 1312 women with early stage breast cancer who underwent breast conserving surgery and postoperative radiotherapy between 1991 and 1998 and who were followed up at two centres in Edinburgh (doi: 10.1038/sj.bjc.6603815). Analysis of the 110 treatable relapses showed that they occurred in 1% to 1.5% of the women in each year of the follow-up period.
But different types of relapse varied in their time scales. The incidence of metastatic relapse peaked at just over 3% a year at two to three years after initial surgery and remained at just
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