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BMJ 2007;334:1143-1146 (2 June), doi:10.1136/bmj.39211.527488.94
Richard Reithinger, epidemiologist1, Karen Megazzini, project director1, Stephen J Durako, vice president1, D Robert Harris, senior epidemiologist1, Sten H Vermund, director2
1 Clinical Trials Area, Westat, Rockville, Maryland, USA, 2 Institute for Global Health, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
Correspondence to: R Reithinger rreithinger@yahoo.co.uk
Many countries are expanding the coverage of programmes to prevent mother to child transmission of HIV. Although the need is unquestionable, Richard Reithinger and colleagues are concerned that without true measures of effectiveness we may not be making the best use of resources
| The first 150 words of the full text of this article appear below. |
In 2006, an estimated 2.3 million children under 15 years were living with HIV and about half a million babies became infected with HIV before birth, during delivery, or through breast feeding.1 Prevention of mother to child transmission of HIV is therefore a priority for agencies fighting the global HIV epidemic, but many questions remain about the effectiveness of the current programmes. We use the President's Emergency Plan for AIDS Relief2 as an example to examine how programmes to prevent mother to child transmission are monitored and evaluated and to highlight the problems.
Estimates of the efficacy of antiretroviral prophylaxis3 suggest that at least half of the world's children who are at risk of HIV infection might be protected if a mother receives antenatal care, is offered HIV counselling and testing, and, if infected, she and her baby receive prophylaxis. Prophylaxis is the mainstay of the strategy to prevent mother
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