BMJ  2007;334 (2 June), doi:10.1136/bmj.39232.418403.43

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Practice, practice, practice

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This week's Practice section has a trio of interesting and useful articles.

Giuseppe Lauria and Raffaella Lombardi review recent advances in the use of skin biopsy to diagnose and monitor peripheral neuropathy (doi: 10.1136/bmj.39192.488125.BE). An easy to perform 3 mm punch biopsy can make the diagnosis of small nerve fiber neuropathies, which can be associated with diabetes and other metabolic disorders, sarcoidosis and other immune-mediated disorders, and viral and hereditary diseases. Commonly recommended nerve conduction studies only evaluate large myelinated fibers. Sural nerve biopsies, used to diagnose peripheral neuropathies, are invasive and sometimes dangerous procedures. Punch biopsy is worth thinking about in patients—especially those with chronic diseases—who complain of burning, prickling sensations or deep and aching foot pains.

In a 10-minute consultation on sinusitis, Neil Chadha and Rashmi Chadha emphasize that the diagnosis of rhinosinusitis is a clinical one, at least in primary care (doi: 10.1136/bmj.39161.557211.47). Characteristic signs . . . [Full text of this article]

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Relevant Articles

Skin biopsy: a new tool for diagnosing peripheral neuropathy

Giuseppe Lauria and Raffaella Lombardi
BMJ 2007 334: 1159-1162. [Extract] [Full Text] [PDF]

Assessment and initial management of feverish illness in children younger than 5 years: summary of NICE guidance

Martin Richardson, Monica Lakhanpaul on behalf of the Guideline Development Group and the technical team
BMJ 2007 334: 1163-1164. [Extract] [Full Text] [PDF]

10-minute consultation: sinusitis

Neil K Chadha and Rashmi Chadha
BMJ 2007 334: 1165. [Extract] [Full Text] [PDF]