BMJ  2007;334:842-846 (21 April), doi:10.1136/bmj.39169.706574.AD

Clinical Review

Clinical review

Delirium in older people

John Young, professor1, Sharon K Inouye, professor2

1 Academic Unit of Elderly Care and Rehabilitation, University of Leeds and Bradford Teaching Hospitals NHS Foundation Trust , 2 Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, and Aging Brain Center, Institute for Aging Research, Hebrew Senior Life, Boston, MA, USA

Correspondence to: Professor J Young, Academic Unit of Elderly Care and Rehabilitation, St Luke's Hospital, Bradford BD5 0NA John.young@bradfordhospitals.nhs.uk

The first 150 words of the full text of this article appear below.

Few ill health situations are more degrading to people of any age than loss of reasoning, faculties, and personhood. These are the unpleasant consequences of delirium—a common condition affecting ill older people, particularly those with some degree of dementia. It is characterised by recent onset of fluctuating inattention and confusion, linked to one or more triggering factors.


SUMMARY POINTS

• Delirium is a common presentation of acute illness in older people
• The development of delirium is associated with adverse outcomes
• Delirium is characterised by recent onset of fluctuating inattention and drowsiness linked to triggering factors
• Routine cognitive assessment in unwell older people would improve detection rates
• Good research evidence exists that, with better systems of routine care, delirium could be prevented in at least a third of patients


Delirium is a major burden to healthcare services and has been largely ignored by health service planners and practitioners.1 Moreover, . . . [Full text of this article]

Sources and selection criteria


How common is delirium?


What are the consequences of delirium?


What are the clinical features of delirium?


Box 1 Criteria for delirium, according to the Diagnostic and Statistical Manual of Mental Disorders (DSM IV)8
Box 2 Hyperactive delirium
Scenario
Features
Box 3 Hypoactive delirium
Scenario
Features

How is delirium diagnosed?


Box 4 Confusion assessment method*13 14
1 Acute onset and fluctuating course
2 Inattention
3 Disorganised thinking
4 Altered level of consciousness

The overlap between delirium and dementia


What are the causes of delirium?


Box 5 Common risk factors and precipitants for delirium
Risk factors
Precipitants (more than one may be present)
Drugs and delirium

Can delirium be prevented?


How can delirium be managed?


Conclusions


ADDITIONAL EDUCATIONAL RESOURCES
Resources for patients
Resources for healthcare professionals

Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?

Related Articles

Approach is now screening, prevention, and recognition
Mehraj Shah, Farida Jan, and Akeem Sule
BMJ 2007 334: 968. [Extract] [Full Text] [PDF]

Delirium should be included in guidelines and curriculums
Alasdair M J MacLullich, John M Starr, and A Peter Passmore
BMJ 2007 334: 968. [Extract] [Full Text] [PDF]

Non-degenerative mild cognitive impairment in elderly people and use of anticholinergic drugs: longitudinal cohort study
Marie L Ancelin, Sylvaine Artero, Florence Portet, Anne-Marie Dupuy, Jacques Touchon, and Karen Ritchie
BMJ 2006 332: 455-459. [Abstract] [Full Text] [PDF]

This article has been cited by other articles:

  • Radtke, F. M., Franck, M., Schneider, M., Luetz, A., Seeling, M., Heinz, A., Wernecke, K. D., Spies, C. D. (2008). Comparison of three scores to screen for delirium in the recovery room. Br J Anaesth 0: aen193v1-6 [Abstract] [Full text]  
  • Feldman, H. H. MD, Jacova, C. PhD, Robillard, A. MD, Garcia, A. MD PhD, Chow, T. MD, Borrie, M. MB ChB, Schipper, H. M. MD PhD, Blair, M. BSc, Kertesz, A. MD, Chertkow, H. MD (2008). Diagnosis and treatment of dementia: 2. Diagnosis. CMAJ 178: 825-836 [Abstract] [Full text]  
  • McManus, J., Pathansali, R., Stewart, R., Macdonald, A., Jackson, S. (2007). Delirium post-stroke. Age Ageing 36: 613-618 [Abstract] [Full text]  
  • Connor, M., Williams, A., Macleod, M., Smith, C. (2007). Vanishing diplopia: a problem case. PN 7: 268-271 [Full text]  
  • Shah, M., Jan, F., Sule, A. (2007). Approach is now screening, prevention, and recognition. BMJ 334: 968-968 [Full text]  
  • MacLullich, A. M J, Starr, J. M, Passmore, A P. (2007). Delirium should be included in guidelines and curriculums. BMJ 334: 968-968 [Full text]  

Rapid Responses:

Read all Rapid Responses

Delirium in older people, systematic screening, prevention and recognition
Mehraj Shah, et al.
bmj.com, 24 Apr 2007 [Full text]
Delirium: a common cause of misdiagnosis in the elderly
Ángel J Romero-Cabrera, et al.
bmj.com, 24 Apr 2007 [Full text]
The unsatisfactory coverage of delirium by NICE, the JCHMT and the Royal Colleges of Physicians
Alasdair MJ MacLullich, et al.
bmj.com, 27 Apr 2007 [Full text]
Delirium management in the acute setting
sunku h guptha
bmj.com, 27 Apr 2007 [Full text]
Drug treatment of delirium
David Meagher
bmj.com, 28 Apr 2007 [Full text]
Delirium in older people
Jatinder K Juss, et al.
bmj.com, 30 Apr 2007 [Full text]
Delirium and emergent EEG
Leonardo Cocito, et al.
bmj.com, 7 May 2007 [Full text]
Post-operative confusion
Michael Patkin
bmj.com, 18 May 2007 [Full text]
Pharmacologic treatment of delirium in older people
Domingo R Hidalgo, et al.
bmj.com, 21 May 2007 [Full text]



Student BMJ

Risk of surgery for inflammatory bowel disease: record linkage studies

What can you learn from this BMJ paper? Read Leanne Tite's Paper+

www.student.bmj.com

Listen to the latest BMJ Interview