Osteoporosis and its management

doi:10.1136/bmj.39050.597350.47

BMJ 2006;333:1251-1256 (16 December), doi:10.1136/bmj.39050.597350.47

Clinical Review

Osteoporosis and its management

Kenneth E S Poole, specialist registrar in rheumatology, Juliet E Compston, professor of bone medicine

¹ Addenbrooke's Hospital, Cambridge CB2 2QQ

Correspondence to: J E Compston jec1001@cam.ac.uk

The first 150 words of the full text of this article appear below.

Fractures caused by osteoporosis affect onein two women and one in five men over the age of 50, resultingin an estimated annual cost to the health services of around£1.8bn ( ${euro}$ 2.7bn; $3.5bn) in the United Kingdom and ${euro}$ 30bnin all of Europe.¹ ² Most patients with osteoporosisare managed in primary care, but a minority will benefit fromreferral to specialised centres. In recent years considerableadvances have been made both in the identification of peopleat high risk of fracture and in therapeutic options to reducethe risk of fracture. This review focuses on these areas andalso on the partnership that is required between primary andsecondary care to optimise the management of patients with osteoporosis.

Osteoporosis results from reduced bone massand disruption of the micro-architecture of bone (fig 1), givingdecreased bone strength and increased risk of fracture, particularlyof the spine, hip, . . . [Full text of this article]

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