BMJ  2006;333:1200-1204 (9 December), doi:10.1136/bmj.39022.462546.80

Clinical Review

Management of hyperglycaemia in type 2 diabetes: the end of recurrent failure?

¹ Diabetes Centre, Department of Endocrinology, VU University Medical Centre, Amsterdam, De Boelelaan 1117, Netherlands, ² Diabetes and Endocrine Unit, Department of Internal Medicine and Specialities, University of Yaounde, Cameroon, ³ Diabetes Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA

The first 150 words of the full text of this article appear below.

The epidemic of type 2 diabetes imposes an enormous and growing burden on health care worldwide. The number of people with type 2 diabetes around the world is estimated to rise from 151 million in 2000 to 300 million by 2025.¹ The recognition that strict glycaemic control can reduce microvascular complications has made the effective treatment of hyperglycaemia a priority.^{2 3 4 5 6} Recently, the diabetes control and complications trial reported that intensive therapy aimed at normoglycaemia has beneficial effects on cardiovascular disease in type 1 diabetes.⁷ In type 2 diabetes, epidemiological data from the UK prospective diabetes study suggest that lowering glycaemia will reduce the risk of cardiovascular disease.⁸ The treatment of hyperglycaemia in type 2 diabetes is complex; combinations of glucose lowering drugs are often needed to achieve and maintain blood glucose at target values. The development of new classes of drugs to lower blood glucose has increased the treatment options . . . [Full text of this article]

CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?

Relevant Articles

How to achieve strict glycaemic control in type 2 diabetes
BMJ 2006 333: 0. [Full Text] [PDF]

New ideas please

Trish Groves
BMJ 2006 333: 0. [Extract] [Full Text] [PDF]

US Highlights

Douglas Kamerow
BMJ 2006 333: 0. [Extract] [Full Text]

Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study

Irene M Stratton, Amanda I Adler, H Andrew W Neil, David R Matthews, Susan E Manley, Carole A Cull, David Hadden, Robert C Turner, and Rury R Holman
BMJ 2000 321: 405-412. [Abstract] [Full Text] [PDF]

This article has been cited by other articles:

• Gulve, E. A. (2008). Exercise and Glycemic Control in Diabetes: Benefits, Challenges, and Adjustments to Pharmacotherapy. ptjournal 88: 1297-1321 [Abstract] [Full text]  
• Goldstein, B. J. (2007). Clinical Translation of "A Diabetes Outcome Progression Trial": ADOPT Appropriate Combination Oral Therapies in Type 2 Diabetes. J. Clin. Endocrinol. Metab. 92: 1226-1228 [Full text]  

Rapid Responses:

Read all Rapid Responses

Beware of the carbs!

Uffe Ravnskov
bmj.com, 8 Dec 2006 [Full text]

HbA1c: Time for a change in a very confusing scale.

Alain Braillon
bmj.com, 9 Dec 2006 [Full text]

Prevent diabetes, don't treat symptoms

Barry A Groves, PhD
bmj.com, 13 Dec 2006 [Full text]

Management of hyperglycaemia in type 2 diabetes: Licensed indications for existing oral hypoglycaemic therapy in the United Kingdom

John R Lindsay, et al.
bmj.com, 10 Dec 2006 [Full text]

Overegging the pudding.

David Leopold
bmj.com, 10 Dec 2006 [Full text]

It's not just science, but also common sense, that supports the use of low-carb diets in the management of diabetes

John P Briffa
bmj.com, 10 Dec 2006 [Full text]

"Sugar Disease"

Melchior Meijer
bmj.com, 12 Dec 2006 [Full text]

Glycaemic control in type 2 diabetic patients and hemorheologic parameters

Larisa I Carrera, et al.
bmj.com, 14 Dec 2006 [Full text]

Role of anti obesity pills in hyperglycaemia

Babulayeb Mukhopadhyay
bmj.com, 15 Dec 2006 [Full text]

Drugs for T2DM: the new are still unproven.

Neil D Burman
bmj.com, 27 Dec 2006 [Full text]

Lifestyle changes have great potential in the prevention and treatment of type 2 diabetes

Matti Uusitupa, et al.
bmj.com, 29 Dec 2006 [Full text]

Online poll

Find out more >>