BMJ  2006;333:1181-1182 (9 December), doi:10.1136/bmj.39050.672639.80

Editorials

Severe community acquired pneumonia

Early switch from intravenous to oral antibiotics is safe and reduces hospital stay

The first 150 words of the full text of this article appear below.

Research into community acquired pneumonia over the past two decades has focused on developing tools to measure the severity of illness and which antibiotics to choose. Several tools can now help clinicians identify patients with severe community acquired pneumonia in clinical settings.¹ In people with severe disease, international guidelines recommend early treatment with broad spectrum antibiotics, which provide cover for atypical pathogens.²

It is less clear how best to manage patients during their stay in hospital. In this week's BMJ, a randomised trial by Oosterheert and colleagues reports the effect of switching from intravenous to oral antibiotics after three days rather than seven days in people with severe community acquired pneumonia.³ Until now, the lack of quality trial data in areas such as route of antibiotic administration, duration of treatment, and assessment of clinical stability has led to a conservative approach to management and prolongation of hospital stay.

The . . . [Full text of this article]

¹ Waikato Hospital, Hamilton, New Zealand 3204, ² Christchurch Hospital, Christchurch, New Zealand 8001

CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    StumbleUpon    Technorati    What's this?

Relevant Articles

US Highlights

Douglas Kamerow
BMJ 2006 333: 0. [Extract] [Full Text]

Effectiveness of early switch from intravenous to oral antibiotics in severe community acquired pneumonia: multicentre randomised trial

Jan Jelrik Oosterheert, Marc J M Bonten, Margriet M E Schneider, Erik Buskens, Jan-Willem J Lammers, Willem M N Hustinx, Mark H H Kramer, Jan M Prins, Peter H Th J Slee, Karin Kaasjager, and Andy I M Hoepelman
BMJ 2006 333: 1193. [Abstract] [Full Text] [PDF]

This article has been cited by other articles:

• (2007). Early Switch to Oral Antibiotics in CAP. JWatch Infect. Diseases 2007: 3-3 [Full text]  

Online poll

Find out more >>