BMJ  2006;332:1315-1319 (3 June), doi:10.1136/bmj.332.7553.1315

Clinical review

Diagnosis and management of gout

Martin Underwood, professor of general practice

Department of General Practice and Primary Care, Centre for Health Sciences, University of London, London E1 2AT. m.underwood@qmul.ac.uk

The first 150 words of the full text of this article appear below.

Introduction

Gout is a common cause of acute arthritis. An ageing population, increasing obesity, and lifestyle changes will render it more common.1 Here I outline the epidemiology of gout, appraise the evidence base for its management, and suggest ways of managing idiopathic gout. Management of hyperuricaemia due to inborn errors of metabolism (for example, Lesch-Nyhan syndrome) and its prevention during cancer chemotherapy are not discussed here.

Sources and selection criteria

The material for this review draws heavily on my chapter on gout in Clinical Evidence and from my work on a recent systematic review of studies on the prevention and treatment of recurrent gout. To ensure that no relevant randomised controlled trials published since the systematic review had been overlooked, I ran a previous search strategy in PubMed and the Cochrane database of systematic reviews. I identified other relevant studies from my personal database of papers on gout, did forward and backward citation tracking from . . . [Full text of this article]

What is gout?

Who gets gout and hyperuricaemia?

How is gout diagnosed?

Treatment of acute gout

Prevention of recurrent gout

Conclusion


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