Diagnosis and management of gout

doi:10.1136/bmj.332.7553.1315

BMJ 2006;332:1315-1319 (3 June), doi:10.1136/bmj.332.7553.1315

Clinical review

Diagnosis and management of gout

Martin Underwood, professor of general practice

Department of General Practice and Primary Care, Centre for Health Sciences, University of London, London E1 2AT. m.underwood@qmul.ac.uk

The first 150 words of the full text of this article appear below.

Introduction

Gout is a common cause of acute arthritis. An ageing population,increasing obesity, and lifestyle changes will render it morecommon.¹ Here I outline the epidemiology of gout, appraise theevidence base for its management, and suggest ways of managingidiopathic gout. Management of hyperuricaemia due to inbornerrors of metabolism (for example, Lesch-Nyhan syndrome) andits prevention during cancer chemotherapy are not discussedhere.

Sources and selection criteria

The material for this review draws heavily on my chapter ongout in Clinical Evidence and from my work on a recent systematicreview of studies on the prevention and treatment of recurrentgout. To ensure that no relevant randomised controlled trialspublished since the systematic review had been overlooked, Iran a previous search strategy in PubMed and the Cochrane databaseof systematic reviews. I identified other relevant studies frommy personal database of papers on gout, did forward and backwardcitation tracking from . . . [Full text of this article]

What is gout?

Who gets gout and hyperuricaemia?

How is gout diagnosed?

Treatment of acute gout

Prevention of recurrent gout

Conclusion

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