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BMJ 2006;332:777-780 (1 April), doi:10.1136/bmj.332.7544.777
Vanessa Jones1, Joseph E Grey, Keith G Harding
1 Vanessa Jones is senior lecturer at the Wound Healing Research Unit, Cardiff University.
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Traditionally wet-to-dry gauze has been used to dress wounds. Dressings that create and maintain a moist environment, however, are now considered to provide the optimal conditions for wound healing. Moisture under occlusive dressings not only increases the rate of epithelialisation but also promotes healing through moisture itself and the presence initially of a low oxygen tension (promoting the inflammatory phase). Gauze does not exhibit these properties; it may be disruptive to the healing wound as it dries and cause tissue damage when it is removed. It is not now widely used in the United Kingdom.
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Occlusive dressings are thought to increase cell proliferation and activity by retaining an optimum level of wound exudate, which contains vital proteins and cytokines produced in response to injury. These
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