BMJ  2006;332:434-435 (25 February), doi:10.1136/bmj.332.7539.434

Editorial

Should obese women with polycystic ovary syndrome receive treatment for infertility?

Given the risks such women will face in pregnancy, they should lose weight first

The first 150 words of the full text of this article appear below.

Polycystic ovaries are seen at ultrasound in 20-25% of women, and the prevalence of polycystic ovary syndrome (PCOS) seems to be rising because of the current epidemic of obesity.1 The syndrome accounts for 90-95% of women who attend infertility clinics with anovulation. The considerable risks in pregnancy associated with obesity are not usually appreciated when patients with PCOS attend clinics and request fertility treatment. Is it appropriate to offer treatment or to insist on weight loss? Or does any overweight woman have the right to receive treatment, irrespective of the possible outcome?

The syndrome is defined by any two out of the following criteria: infrequent or absent menstruation, indicating anovulation; hyperandrogenism; and polycystic ovaries diagnosed by ultrasound after the exclusion of other aetiologies of menstrual disturbance and hyperandrogenism.2 At least 40% of women with PCOS are obese,1 and they are more insulin resistant than weight matched women with normal . . . [Full text of this article]

Adam H Balen, professor of reproductive medicine and surgery

General Infirmary, Leeds LS2 9NS
(adam.balen@leedsth.nhs.uk)

Martin Dresner, consultant anaesthetist, Eleanor M Scott, senior lecturer in diabetes and endocrinology, James O Drife, professor of obstetrics and gynaecology

General Infirmary, Leeds LS2 9NS


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This article has been cited by other articles:

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Rapid Responses:

Read all Rapid Responses

Re: Should obese women with polycystic ovary syndrome receive treatment for infertility?
Sheila E. Laredo
bmj.com, 25 Feb 2006 [Full text]
Lifestyle modification is central to management
Jonathan M Lord, et al.
bmj.com, 1 Mar 2006 [Full text]
Increase in POCS and obesity due to young-age use of progesterones?
Ellen C G Grant
bmj.com, 2 Mar 2006 [Full text]



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