Inhaled insulin is approved in Europe and United States

doi:10.1136/bmj.332.7537.321

BMJ 2006;332:321 (11 February), doi:10.1136/bmj.332.7537.321

News

Inhaled insulin is approved in Europe and United States

Jeanne Lenzer

New York

The first 150 words of the full text of this article appear below.

An inhaled form of human insulin, Exubera, has been approvedin Europe and the United States for the treatment of type 1and 2 diabetes in adults. The drug, to be marketed jointly byPfizer and Sanofi-Aventis, was hailed by the US Food and DrugAdministration as the "first new insulin delivery option introducedsince the discovery of insulin in the 1920s."

Both the FDA and the European Agency for the Evaluation of MedicinalProducts have specified that the drug, which will not be availablefor several months, is contraindicated in smokers and in patientswho have smoked in the preceding six months. It is "not recommended"in patients with asthma, bronchitis, or emphysema.

The European agency has also specified that Exubera is indicatedonly for "adult patients with type 2 diabetes mellitus not adequatelycontrolled with oral antidiabetic agents and requiring insulintherapy" or for patients with type 1 . . . [Full text of this article]

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