BMJ  2006;332:215-219 (28 January), doi:10.1136/bmj.332.7535.215

Clinical review

Venous thromboembolism

¹ Haemostasis, Thrombosis and Vascular Biology Unit, University Department of Medicine, City Hospital, Birmingham B18 7QH

The first 150 words of the full text of this article appear below.

Introduction

Venous thrombosis is the process of clot (thrombus) formation within veins. Although this can occur in any venous system, the predominant clinical events occur in the vessels of the leg, giving rise to deep vein thrombosis, or in the lungs, resulting in a pulmonary embolus. Collectively referred to as venous thromboembolism, these have a high prevalence both in the community and in hospitals, and bring a considerable burden of morbidity and possible mortality.

The causes of venous thromboembolism can be hereditary or acquired. A risk factor for thrombosis often can be identified in over 80% of patients, but usually more than one factor is at play in a patient.

Sources and selection criteria

Our information came from a personal collection of published work and searches of Medline using the key words "venous thromboembolism", "deep vein thrombosis," and "pulmonary embolus". We also reviewed recent guidelines on management of venous thromboembolism and identified several relevant Cochrane . . . [Full text of this article]

Deep vein thrombosis

Pulmonary embolism

Who is at risk of venous thromboembolism?

Pathophysiology of venous thromboembolism

Prevention and treatment of venous thromboembolism

Low molecular weight heparin
Vitamin K antagonists
Fondaparinux
Thrombolytic therapy
Non-drug treatments

The future

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This article has been cited by other articles:

• Stassen, P. M., Derks, R. P. H., Kallenberg, C. G. M., Stegeman, C. A. (2008). Venous thromboembolism in ANCA-associated vasculitis--incidence and risk factors. Rheumatology (Oxford) 47: 530-534 [Abstract] [Full text]  
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