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BMJ 2005;331:1025 (29 October), doi:10.1136/bmj.331.7523.1025
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EDITORJoppi et al's critique and not biotech itself is disappointing.1
The authors classified most of the biotech drugs (24/61) as "copycat or me too products"pejorative terms intended to cast prejudicial doubt on a drug's value. I am familiar with one of the drugs on the copycat list, teriparatide (rhPTH1-34, Forteo, Eli Lilly), a treatment for osteoporosis. I helped with its development. Teriparatide was the first and remains the only drug in its class approved for osteoporosis. It was the first bone anabolic agent ever widely approved in Europe. Many experts have deemed teriparatide an important addition to the treatment options for osteoporosis. If an obviously pioneering innovation such as teriparatide may be classified by Joppi et al as a copycat, one must question all drugs on the "copycat" list.
Four of the 15 innovative drugs classified by Joppi et al were for orphan diseases, which by definition affect
Fredric J Cohen, president
Pharma Growth Strategies LLC, 3331 Street Road, Suite 140, Bensalem, PA 19020, USA fred@pharmagrowth.com
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