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BMJ 2005;331:638 (17 September), doi:10.1136/bmj.331.7517.638-b
| The first 100% of the full text of this article appears below. |
EditorGlymour and Kawachi suggest a modest proposal to reduce publication bias, reviewed by Dubben and Beck-Bornholdt.1 Their suggestion is indeed modest because many statistically insignificant or negative studies are not necessarily submitted to a medical journal for publication.
The only effective solution would be mandatory registration of all trials in a centralised website before the trial starts, with mandatory publication of the raw data on that centralised website irrespective of whether the trialists submit their results to a medical journal for publication. That solution would allow meta-analysts to collect data from all relevant studies and not only studies published in medical journals.
Jeffrey Mann, retired physician
Salt Lake City, UT 84103, USA jmannemg@earthlink.net