BMJ  2005;330:1363-1364 (11 June), doi:10.1136/bmj.38429.473310.AE (published 15 April 2005)

Paper

Use of waist circumference to predict insulin resistance: retrospective study

¹ Department of Medicine M61, Karolinska Institutet at Karolinska University Hospital, Huddinge, SE-141 86 Stockholm, Sweden, ² Department of Clinical Physiology, Karolinska Institutet at Karolinska University Hospital

The first 150 words of the full text of this article appear below.

Introduction

Insulin resistance is an important pathogenic factor in common metabolic disorders. No easy clinical test exists for predicting the insulin resistance of an individual. We assessed how effectively different anthropometric measurements and biochemical markers used in clinical practice can predict insulin sensitivity.

Participants, methods, and results

We analysed a sample of 2746 healthy volunteers (798 male) from retrospectively collected data. Ages ranged from 18 years to 72 years, body mass index (kg/m²) from 18 to 60, and waist circumferences from 65 cm to 150 cm (see table A on bmj.com for further data). We determined height, weight, waist circumference (mid-way between the lateral lower ribs and the iliac crest), and hip circumference. Results from analyses of venous plasma for glucose, insulin, lipids, and leptin concentrations were used. We used homoeostasis model assessment (HOMA index) as a measure of insulin sensitivity (plasma glucose (mol/l) x plasma insulin (mU/l)/22.5)—an established test in epidemiological studies.¹ We . . . [Full text of this article]

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