BMJ  2005;330:999-1000 (30 April), doi:10.1136/bmj.38377.715799.F7 (published 18 March 2005)

Paper

Opportunity cost of antidepressant prescribing in England: analysis of routine data

Sandra Hollinghurst, lecturer in health economics1, David Kessler, general practitioner research fellow1, Tim J Peters, professor of primary care health services research1, David Gunnell, professor of epidemiology2

1 Academic Unit of Primary Health Care, Department of Community Based Medicine, University of Bristol, Bristol BS6 6JL, 2 Department of Social Medicine, University of Bristol, Bristol BS8 2PR

Correspondence to: S P Hollinghurst s.p.hollinghurst@bristol.ac.uk

The first 150 words of the full text of this article appear below.

Introduction

Recently, prescribing of antidepressant drugs has increased exceptionally.1 At the same time, concerns have been raised about the medicalisation of human distress and, more recently, about the safety of antidepressants.1

Many general practitioners would like to refer patients for psychological treatment, for which there is good evidence of effectiveness,2 but are constrained by the lack of NHS therapists. We estimated the opportunity cost of the recent rise in antidepressant prescribing by valuing it in terms of an effective alternative treatment—cognitive behaviour therapy.

Methods and results

We used Department of Health data on the number and cost of antidepressant drugs dispensed in the community in England to quantify the changes between 1991 and 2002. The baseline year (1991) was chosen to ensure a meaningful timescale and to cover a period of consistent approaches to recording. We took population statistics from www.statistics.gov.uk/statbase, and applied an inflation rate of 32% (from www.statistics.gov.uk/rpi) to 1991 . . . [Full text of this article]

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