BMJ  2005;330:45 (1 January), doi:10.1136/bmj.330.7481.45-a

Letter

Placebos in medicine

Medical paradoxes need disentangling

The first 150 words of the full text of this article appear below.

EDITOR—As Spiegel's editorial highlights,1 paradoxes around the placebo effect can be overcome by distinguishing between a dummy pill and the effects of thoughts, feelings, and human relationships.2

Placebos may seem like a less toxic solution than pharmacological treatments for functional or chronic conditions but this carries side effects—disrupt trust, and outcome is disturbed. Doctors in Israel give placebo treatments without informing their patients, at trial closure investigators often don't tell people if they got placebo,3 and patients often turn to complementary medicine without informing their doctors.

The issue should not be about prescribing placebos but rather about the need to increase our general knowledge around healing mechanisms,4 to harness directly what placebo harnesses indirectly, in an ethical and practical manner, encouraging a sense of trust and partnership between the public and healthcare specialists.

Placebo effect research presents evidence of the extent to which individuals possess natural self healing . . . [Full text of this article]

Zelda Di Blasi, postdoctoral fellow

University of California San Francisco, San Francisco, CA 94143, USA DiBlasi@ocim.ucsf.edu

David Reilly, consultant physician

Centre for Integrative Care, Glasgow Homeopathic Hospital, Glasgow


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