BMJ  2004;329:1163-1166 (13 November), doi:10.1136/bmj.329.7475.1163

Education and debate

Expanding antiretroviral therapy in Malawi: drawing on the country's experience with tuberculosis

Anthony D Harries, technical assistant in HIV care and support1, Edwin Libamba, head of unit1, Erik J Schouten, technical assistant in HIV/AIDS coordination1, Andrina Mwansambo, medical officer in HIV care and support4, Felix M Salaniponi, director2, Rex Mpazanje, director3

1 HIV/AIDS Unit, Ministry of Health, PO Box 30377, Lilongwe, Malawi, 2 National Tuberculosis Control Programme, Ministry of Health, Malawi, 3 Department of Clinical Services, Ministry of Health, Malawi, 4 National AIDS Commission, Lilongwe, Malawi

Correspondence to: A D Harries adharries@malawi.net

The DOTS ("directly observed treatment, short course") strategy has been successfully used in developing countries to provide effective control of tuberculosis. Field workers in Malawi are promoting the same approach for HIV infection through the expansion of highly active antiretroviral therapy

The first 150 words of the full text of this article appear below.

Introduction

Highly active antiretroviral therapy (HAART) must be expanded in sub-Saharan Africa, where the HIV/AIDS epidemic is taking an appalling toll. Malawi, a small, poor African country, is expanding HAART nationally. The "directly observed treatment, short course" (DOTS) strategy has been successfully used for years to provide effective national control of tuberculosis, and the same concepts are being applied for delivering HAART. We describe how the principles of standardised case finding, standardised treatment regimens, regular monitoring and evaluation, and uninterrupted supplies of drugs can be used to deliver HAART. If implemented well, these principles should ensure a controlled delivery system, which would reduce the risks of inconsistent prescribing practices and the development of drug resistance.

Response to Malawi's HIV/AIDS epidemic

In 2003 sub-Saharan Africa had an estimated 3.4 million new cases of HIV infection and up to 2.4 million deaths.1 Malawi has one of the highest HIV/AIDS prevalence rates in sub-Saharan Africa, with 14% of those . . . [Full text of this article]

Fast countrywide expansion of HAART

Learning from tuberculosis control

-->

Framework for delivering antiretrovirals

Eligibility criteria for treatments when resources are limited

Standardised antiretroviral therapy

Registration, recording, and reporting

Conclusion


Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?

Relevant Articles

The power of women, community, and Bob Geldof
Kamran Abbasi
BMJ 2004 329: 0. [Extract] [Full Text] [PDF]

Poor countries make the best teachers: discuss
Tessa Richards and James Tumwine
BMJ 2004 329: 1113-1114. [Extract] [Full Text] [PDF]

Highly active antiretroviral therapy
Peter Mugyenyi
BMJ 2004 329: 1118-1119. [Extract] [Full Text] [PDF]

This article has been cited by other articles:

  • Beadles, W I, Jahn, A, Weigel, R, Clutterbuck, D (2009). Peripheral neuropathy in HIV-positive patients at an antiretroviral clinic in Lilongwe, Malawi. Trop Doct 39: 78-80 [Abstract] [Full text]  
  • Makombe, S. D, Harries, A. D, Kwong-Leung Yu, J., Hochgesang, M., Mhango, E., Weigel, R., Pasulani, O., Fitzgerald, M., Schouten, E. J, Libamba, E. (2008). Outcomes of patients with Kaposi's sarcoma who start antiretroviral therapy under routine programme conditions in Malawi. Trop Doct 38: 5-7 [Abstract] [Full text]  
  • Hosseinipour, M. C., Neuhann, F. H., Kanyama, C. C., Namarika, D. C., Weigel, R., Miller, W., Phiri, S. J. P. (2006). Lessons Learned From a Paying Antiretroviral Therapy Service in the Public Health Sector at Kamuzu Central Hospital, Malawi: 1-Year Experience. J Int Assoc Physicians AIDS Care (Chic Ill) 5: 103-108 [Abstract]  
  • Stringer, J. S. A., Zulu, I., Levy, J., Stringer, E. M., Mwango, A., Chi, B. H., Mtonga, V., Reid, S., Cantrell, R. A., Bulterys, M., Saag, M. S., Marlink, R. G., Mwinga, A., Ellerbrock, T. V., Sinkala, M. (2006). Rapid scale-up of antiretroviral therapy at primary care sites in Zambia: feasibility and early outcomes.. JAMA 296: 782-793 [Abstract] [Full text]  
  • Mugyenyi, P. (2004). Highly active antiretroviral therapy. BMJ 329: 1118-1119 [Full text]  



Access jobs at BMJ Careers
Whats new online at Student 

BMJ