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BMJ 2004;329:715 (25 September), doi:10.1136/bmj.329.7468.715
T J Cole, professor of medical statistics1
1 Centre for Paediatric Epidemiology and Biostatistics, Institute of Child Health, London WC1N 1EH tim.cole@ich.ucl.ac.uk
| The first 150 words of the full text of this article appear below. |
"You can't teach an old dogma new tricks"
Dorothy Parker
Dogs are widely recognised as smelling smells that humans miss. Yet the idea of turning this canine skill to clinical diagnosis is novel. The study by Willis et al takes a first cautious step in testing such an idea by training dogs to detect bladder cancer from urine samples and then seeing if their detection rate when tested blind is better than expected by chance.1
The design of the trial was simple and elegant. Six dogs were trained to recognise urine samples from patients with bladder cancer compared with diseased and healthy sex matched controls. Each dog was then offered a set of seven urine samples, from a person with cancer and six controls, and they identified the sample they considered to be different by lying next to it. This process was repeated eight times, so each dog effectively rolled
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