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BMJ 2004;329:569-570 (4 September), doi:10.1136/bmj.329.7465.569-b
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EDITORIf the new British Hypertension Society (BHS) guidelines1 are evidence based I'll eat my ALLHAT.2 This and other evidence points to thiazide-type diuretics as the initial treatment of choice. New US guidelines reflect this,3 but the BHS recommends a range of initial drug types for hypertension.
The BHS recommends primary prevention use of statins for those with sustained "starting" blood pressure > 140 mm Hg systolic or > 90 mm Hg diastolic, or both, and an estimated risk of cardiovascular disease > 20% over the next 10 years. The set target is to lower total cholesterol by 25% or low density lipoprotein cholesterol by 30% or to reach < 4.0 mmol/l or < 2.0 mmol/l respectively, whichever is the greater.
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Where is the evidence? The BHS cites Scandinavian cardiac outcomes trial-lipid lowering arm (ASCOT-LLA)4 and the heart protection study.5 In ASCOT-LLA subjects were
Martin G Duerden, general practitioner
Meddygfa Gyffin, Conwy, North Wales LL32 8LT martin@theduerdens.co.uk