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BMJ 2004;328:1438 (12 June), doi:10.1136/bmj.328.7453.1438-b
| The first 150 words of the full text of this article appear below. |
EDITORI have some concerns about the article on managing nocturia by Marinkovic et al.1
Firstly, claiming that melatonin is effective in men with nocturia is misleading. The study quoted included only 20 patients. The authors themselves say that the clinical importance of melatonin is uncertain.
Secondly, for an article entitled a clinical review, little mention is made of the common causes or treatments of nocturiafor example, bladder overactivity, prostatic disease, and urinary tract infection
Thirdly, sacral neuromodulation is not a widely suitable and recognised treatment for nocturia. It is very expensive. The success rate of 85% quoted does not reflect the literature. On an intention to treat basis the overall success rates are in the order of 33% (similar to a placebo response). Nocturia itself is evaluated only as a secondary end point in most studies on neuromodulation. It is an important research tool, studied and used in
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Roger Walker, consultant urologist
Christchurch, New Zealand 4710 bigrog@freeuk.com