BMJ  2004;328:503 (28 February), doi:10.1136/bmj.328.7438.503

Clinical review

Interactive case report

Treating nausea and vomiting during pregnancy: case outcome

¹ Dean Lane Family Practice, Bedminster, Bristol, ² Division of Primary Health Care, University of Bristol, ³ Tayside Centre for General Practice, University of Dundee, Dundee DD2 4AD

The first 150 words of the full text of this article appear below.

Five weeks ago (31 January, p 276) we presented the case of Ms Reynolds, a 25 year old woman who presented to her general practitioner when eight weeks pregnant complaining of nausea and vomiting with light headedness.After an unsuccessful trial of prochlorperazine, she asked about alternatives to conventional drugs, and we suggested a trial of vitamin B-6 (pyridoxine) to relieve her symptoms (7 February, p 337). Because of the paucity of evidence for or against the use of vitamin B-6, we suggested an n of 1 trial as an objective way to assess whether it was effective. The table shows that vitamin B-6 did not have a significant treatment effect compared with placebo for Ms Reynolds's four most important symptoms. After being shown the results of her n of 1 study, Ms Reynolds stopped taking vitamin B-6.

View this table: [in this window] [in a new window]   Main symptom scores* for nausea and vomiting in pregnancy after five . . . [Full text of this article]

 

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