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BMJ 2003;327:1349 (6 December), doi:10.1136/bmj.327.7427.1349
| The first 150 words of the full text of this article appear below. |
EditorChalmers et al highlight from their survey of non-commercial randomised trials the challenges faced by researchers seeking funding for trials addressing issues that are not of interest to industry.1
For any large multicentre clinical trial to reach its target accrual, the clinical research community must be committed to the trial at the earliest stages of its development. Current financing of peer reviewed trials by the Department of Health and the Medical Research Council begins only once a full proposal is approved. However, costs are incurred in the process of developing a full proposal, particularly by national meetings to discuss and develop the detailed protocol and the administrative support for revisions of the text.
Although much of the communication between clinicians can be done by email, meetings of clinicians face to face are needed to debate the research question and practicalities for a clinical trial. In a trial supported by industry
Ian H Kunkler, consultant
Western General Hospital, Edinburgh EH4 2XU I.Kunkler@ed.ac.uk