BMJ  2003;327:794-798 (4 October), doi:10.1136/bmj.327.7418.794

Clinical review

Basal cell carcinoma

C S M Wong, specialist registrar in dermatology1, R C Strange, professor in clinical biochemistry2, J T Lear, consultant dermatologist1

1 Dermatology Centre, University of Manchester, Hope Hospital, Salford, Manchester M6 8HD, 2 Keele University Medical School, North Staffordshire Hospital, Stoke-on-Trent, Staffordshire

Correspondence to: J T Lear lisa.redfern@ccmmc.nhs.uk

The authors of this review aim to provide a comprehensive overview of basal cell carcinoma, concentrating in particular on incidence, risk factors, molecular genetics, clinical features, and treatment

The first 150 words of the full text of this article appear below.

Introduction

Basal cell carcinoma is the most common malignancy in white people.1 Its incidence is increasing worldwide by up to 10% a year. Although mortality is low as basal cell carcinoma rarely metastasises, this malignancy causes considerable morbidity and places a huge burden on healthcare services worldwide. Furthermore, people who have this condition are at high risk of developing further basal cell carcinoma and other malignancies. This review aims to present a concise and comprehensive overview of this important condition, concentrating on recent advances in our understanding of its epidemiology, clinical features, molecular genetics, and treatment.

Sources and selection criteria

This review is based on information obtained from a recent Medline search with basal cell carcinoma, rodent ulcer, and non-melanoma skin cancer as key words. We also used our extensive knowledge of the literature on basal cell carcinoma. We attached greater importance to more recent studies.

Incidence

The incidence of basal cell carcinoma shows marked geographical . . . [Full text of this article]

Risk factors

Molecular genetics

Clinical features

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Treatment

Follow up and prevention


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