BMJ 2003;327:794-798 (4 October), doi:10.1136/bmj.327.7418.794
Clinical review
Basal cell carcinoma
C S M Wong, specialist registrar in dermatology1,
R C Strange, professor in clinical biochemistry2,
J T Lear, consultant dermatologist1
1 Dermatology Centre, University of Manchester, Hope Hospital, Salford, Manchester M6 8HD,
2 Keele University Medical School, North Staffordshire Hospital, Stoke-on-Trent, Staffordshire
Correspondence to: J T Lear lisa.redfern@ccmmc.nhs.uk
The authors of this review aim to provide a comprehensive overview of basal cell carcinoma, concentrating in particular on incidence, risk factors, molecular genetics, clinical features, and treatment
| The first 150 words of the full text of this article appear below. |
Introduction
Basal cell carcinoma is the most common malignancy in white
people.
1 Its incidence is increasing worldwide by up to 10%
a year. Although mortality is low as basal cell carcinoma rarely
metastasises, this malignancy causes considerable morbidity
and places a huge burden on healthcare services worldwide. Furthermore,
people who have this condition are at high risk of developing
further basal cell carcinoma and other malignancies. This review
aims to present a concise and comprehensive overview of this
important condition, concentrating on recent advances in our
understanding of its epidemiology, clinical features, molecular
genetics, and treatment.
Sources and selection criteria
This review is based on information obtained from a recent Medline
search with basal cell carcinoma, rodent ulcer, and non-melanoma
skin cancer as key words. We also used our extensive knowledge
of the literature on basal cell carcinoma. We attached greater
importance to more recent studies.
Incidence
The incidence of basal cell carcinoma shows marked geographical
. . . [Full text of this article]
Risk factors
Molecular genetics
Clinical features
-->-->-->-->
Treatment
Follow up and prevention

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