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BMJ 2003;327:631-632 (20 September), doi:10.1136/bmj.327.7416.631
So many years, and yet we do not know if steroids should be used
| The first 150 words of the full text of this article appear below. |
Rheumatic fever is a delayed complication of pharyngeal infection with group
haemolytic streptococci. Susceptible individuals develop a diffuse inflammatory disease of the heart, joints, brain, blood vessels, and subcutaneous tissue. Carditis is the most serious manifestation of the disease. It may culminate in chronic valvular disease and can lead to heart failure and ultimately death. The incidence of acute rheumatic fever has declined in industrialised countries since the 1950s. However, a resurgence of the disease has been noted, and new epidemics have been reported in the United States.1 Acute rheumatic fever continues to be an important cause of acquired heart disease in developing countries where it is an endemic disease.2 Open heart surgery may be needed to repair or replace heart valves in patients with severely damaged valves, the cost of which is exorbitant and a drain on the meagre health resources of poor countries.
Because of substantial evidence pointing
Antoinette Cilliers, paediatric cardiologist
CH Baragwanath Hospital, PO Box 2588, Northcliff, 2115, Johannesburg, South Africa (amcilliers@icon.co.za)
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