BMJ  2003;327:608-609 (13 September), doi:10.1136/bmj.327.7415.608

Clinical review

Lesson of the week

Spurious hyperglycaemia and icodextrin in peritoneal dialysis fluid

Stephen G Riley, specialist registrar1, James Chess, locum appointment for training1, Kieron L Donovan, consultant nephrologist1, John D Williams, consultant nephrologist1

1 Institute of Nephrology, University Hospital of Wales, Heath Park, Cardiff CF14 4XN

Correspondence to: S G Riley steveriley65@hotmail.com

The first 150 words of the full text of this article appear below.

Introduction

Diabetes mellitus, in particular type 2, has become more common, and the trend is likely to continue.1 Associated comorbidity is also more common—for example, diabetes is now the most common cause of dialysis dependent renal failure in the Western world.2 In the United Kingdom between 1991 and 1998, the incidence of new patients on dialysis increased from 67 to more than 90 patients per million population, and the prevalence of diabetes in people receiving dialysis has increased from 16% to 19%.3

The increasing demand for dialysis and slower growth in capacity for haemodialysis has reinforced the need for an integrated approach to providing dialysis. Peritoneal dialysis is the preferred option for a proportion of patients with end stage renal failure.4 A subgroup of patients has difficulties with removing fluid. This can be improved with an alternative osmotic agent based on a polymer of glucose—icodextrin.5 We report a severe potentially clinical . . . [Full text of this article]

Case report

Discussion


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This article has been cited by other articles:

  • Flore, K. M.J., Delanghe, J. R. (2009). ANALYTICAL INTERFERENCES IN POINT-OF-CARE TESTING GLUCOMETERS BY ICODEXTRIN AND ITS METABOLITES: AN OVERVIEW. pdi 29: 377-383 [Abstract] [Full text]  
  • Power, A, Duncan, N, Goodlad, C (2009). Management of the dialysis patient for the hospital physician. Postgrad. Med. J. 85: 376-381 [Abstract] [Full text]  
  • Galante, O., Abriel, A., Avnun, L. S, Rugachov, B., Almog, Y. (2009). Severe unrecognised hypoglycaemia presenting as pseudonormoglycaemia and unexplained coma in two patients with renal failure. BMJ Case Reports 2009: bcr0720080416-bcr0720080416 [Abstract] [Full text]  
  • Kroll, H. R., Maher, T. R. (2007). Significant Hypoglycemia Secondary to Icodextrin Peritoneal Dialysate in a Diabetic Patient. Anesth. Analg. 104: 1473-1474 [Abstract] [Full text]  

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“Pseudohyperglycaemia” in diabetic patients on peritoneal dialysis
Samson O Oyibo, et al.
bmj.com, 28 Sep 2003 [Full text]
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