BMJ  2003;327:603 (13 September), doi:10.1136/bmj.327.7415.603

Primary care

Eradication of Helicobacter pylori and use of antisecretory drugs: population based cohort study

Annmarie Lassen, senior registrar1, Jesper Hallas, consultant1, Ove B Schaffalitzky de Muckadell, professor2

1 Department of Medical Gastroenterology, Odense University Hospi tal, DK-5000, Denmark, 2 Department of Internal Medicine, Odense University Hospital

Correspondence to: A Lassen annmarie.lassen@ouh.fyns-amt.dk

The first 150 words of the full text of this article appear below.

Introduction

Helicobacter pylori is an important risk factor for peptic ulcers. If infection with H pylori is cured, ulcers associated with H pylori do not recur. An H pylori "test and treat" strategy for patients with peptic ulcers having long term antisecretory treatment has been suggested, in the hope that eradicating H pylori would curtail the rising use of antiulcer drugs.1 2 We describe the long term effect of eradicating H pylori on the use of antiulcer medication in a population of patients with peptic ulcers.

Participants, methods, and results

We included all patients in the Danish county of Funen (population 470 000) who redeemed their first prescription for eradicating H pylori between 1 January 1992 and 31 December 1996 and who had uncomplicated peptic ulcers endoscopically verified before or at the date of redeeming this prescription.

We drew data on gastroscopically and endoscopically verified diagnoses of peptic ulcers (from 1 January 1974) and on prescriptions . . . [Full text of this article]

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Eradication of Helicobacter pylori and use of antisecretory drugs: population based cohort study
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bmj.com, 22 Sep 2003 [Full text]
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