BMJ 2003;326:396 ( 15 February )

Letters

Assortative mating may explain spouses' risk of same disease

The first 150 words of the full text of this article appear below.

EDITOR---Hippisley-Cox et al observed significant similarities for disease between spouses in a large sample of 8386 couples recruited through general practice.1 They think that shared environmental factors may cause these similarities but reject assortative mating as an explanation.

In a sample from the Netherlands twin register we could not replicate their spouse similarities for asthma, depression, diabetes, and cardiovascular disease, possibly because of our smaller sample size of 2152 spouse pairs.2 When we examined health behaviour in a larger sample we found good associations between spouses for smoking, alcohol problems, and exercise behaviour, even after controlling for age and body mass index of both spouses.

The duration of the relationship influenced these associations between spouses (figure). Except for alcohol problems, spouse similarities in health behaviour decreased as the duration of the relationship increased. This implies that assortment for these factors is based on similarity at the time dating began3 and . . . [Full text of this article]


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