Prevalence of gastroschisis at birth: retrospective study

doi:10.1136/bmj.325.7377.1389

BMJ 2002;325:1389-1390 ( 14 December )

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Prevalence of gastroschisis at birth: retrospective study

Gian Luca Di Tanna, senior statistician ^a, Aldo Rosano, senior researcher ^b, Pierpaolo Mastroiacovo, director ^a.

^a International Centre for Birth Defects, 00195 Rome, Italy, ^b Italian Institute of Social Medicine, 00196 Rome

Correspondence to: P Mastroiacovo
icbd@icbd.org

The first 150 words of the full text of this article appear below.

Gastroschisis is a congenital defect of the abdominal wall, characterised by herniation of abdominal viscera outside the abdominalcavity through a defect in the abdominal wall to the side of theumbilicus.¹ Recent studies showed an increase in the prevalenceof gastroschisis at birth but gave no convincing explanation. ² ³ We describe the temporal and geographical variation in this prevalence,using data from the International Clearinghouse For Birth DefectsMonitoring Systems, founded in 1974, which fosters sharing informationand collaboration among the programmes that monitor birth defectsworldwide. Currently, 36 programmes from Europe, the Americas,Asia, Australia, and South Africa participate in the clearinghouseand cumulatively monitor 3.3 million births each year. The headoffice of the clearinghouse, the International Centre for BirthDefects, registers and evaluates thesedata.

Participants, methods, and results

We selected registries that provided information on at least 10 consecutive years including 1998 and analysed births occurringbetween 1974 and 1998 from 19 registries (see bmj.com). The numeratorsof . . . [Full text of this article]

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