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Edward D Chan Department of
Medicine, National Jewish Medical and Research Center, Denver, CO
80206, USA Correspondence to: E D Chan K613E, National
Jewish Medical and Research Center, 1400 Jackson St, Denver, CO 80206, USA chane@njc.org
| The first 150 words of the full text of this article appear below. |
Instigating effective treatment regimens in a way that improves patient adherence is vital to tackling the global resurgence of tuberculosis
About one third of the world's population has latent
tuberculosis, caused by Mycobacterium tuberculosis
infection.1 From this pool, roughly 9 million cases
of active tuberculosis emerge annually, resulting in 2-3 million
deaths. Most new cases occur in the most populated nations
India and
China
but the highest rates of disease are seen in sub-Saharan Africa,
the Indonesian and Philippine archipelagos, Afghanistan, Bolivia, and
Peru. In these regions case rates typically exceed 300 cases per
100 000 per year.
1 2
Although the incidence of
tuberculosis declined in North America and western Europe throughout
most of the latter half of the 20th century, case rates have increased
over the past 10 years mainly because of immigration, HIV/AIDS, and the
neglect of tuberculosis control programmes.
3 4
One vital
factor in curbing the increase of tuberculosis is the instigation of
proper
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