BMJ 2002;325:1282-1286 ( 30 November )

Clinical review

Current medical treatment for tuberculosis

Edward D Chan, assistant professor of medicineMichael D Iseman, professor of medicine

Department of Medicine, National Jewish Medical and Research Center, Denver, CO 80206, USA

Correspondence to: E D Chan K613E, National Jewish Medical and Research Center, 1400 Jackson St, Denver, CO 80206, USA chane@njc.org

The first 150 words of the full text of this article appear below.

Instigating effective treatment regimens in a way that improves patient adherence is vital to tackling the global resurgence of tuberculosis

About one third of the world's population has latent tuberculosis, caused by Mycobacterium tuberculosis infection.1 From this pool, roughly 9 million cases of active tuberculosis emerge annually, resulting in 2-3 million deaths. Most new cases occur in the most populated nations---India and China---but the highest rates of disease are seen in sub-Saharan Africa, the Indonesian and Philippine archipelagos, Afghanistan, Bolivia, and Peru. In these regions case rates typically exceed 300 cases per 100 000 per year. 1 2 Although the incidence of tuberculosis declined in North America and western Europe throughout most of the latter half of the 20th century, case rates have increased over the past 10 years mainly because of immigration, HIV/AIDS, and the neglect of tuberculosis control programmes. 3 4 One vital factor in curbing the increase of tuberculosis is the instigation of proper . . . [Full text of this article]


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