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Off-pump coronary artery bypass grafting may be associated with lesser postoperative neurocognitive impairment
| The first 150 words of the full text of this article appear below. |
Coronary artery bypass grafting is highly effective in improving the quality of life for patients with ischaemic heart disease and the life expectancy for certain anatomical patterns of ischaemic heart disease. Consequently, coronary artery bypass grafting is currently perhaps one of the most commonly performed major operations in the industrialised world; more than a million procedures are performed worldwide every year. Unfortunately subtle impairment of cognitive function is common after surgery and may be related to cardiopulmonary bypass at the time of surgery.
Over the past decade advances in anaesthesia, surgery, and
perioperative management of patients resulted in mortality of coronary artery bypass grafting remaining at 2-3% despite a marked increase in
the risk profile of such procedures. Brain injury is now the most
feared complication of coronary artery bypass grafting and occurs in
two forms.1 Although clinically overt cerebral injury is
infrequent (around 3% of patients have a stroke)
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