BMJ 2002;325:1212-1213 ( 23 November )

Papers

Cannabis use in adolescence and risk for adult psychosis: longitudinal prospective study

Papers pp 1195, 1199

Louise Arseneault, lecturer ^a, Mary Cannon, Wellcome Trust advanced fellow ^b, Richie Poulton, director, Dunedin multidisciplinary health and development study ^c, Robin Murray, professor ^b, Avshalom Caspi, professor ^a, Terrie E Moffitt, professor ^a. 

^a SGDP Research Centre, King's College, London SE5 8AF, ^b Division of Psychological Medicine, King's College, ^c Dunedin Multidisciplinary Health and Development Research Unit, University of Otago, Dunedin, New Zealand

Correspondence to: T E Moffitt t.moffitt@iop.kcl.ac.uk

The first 150 words of the full text of this article appear below.

The strongest evidence that cannabis use may be a risk factor for later psychosis comes from a Swedish cohort study which found that heavy cannabis use at age 18 increased the risk of later schizophrenia sixfold. ^{1 2} This study could not establish whether adolescent cannabis use was a consequence of pre-existing psychotic symptoms rather than a cause. We present the first prospective longitudinal study of adolescent cannabis use as a risk factor for adult schizophreniform disorder, taking into account childhood psychotic symptoms³ antedating cannabis use.

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	Methods and results

The Dunedin multidisciplinary health and development study (a study of a general population birth cohort of 1037 individuals born in Dunedin, New Zealand, in 1972-3)⁴ has a 96% follow up rate at age 26. It obtained information on psychotic symptoms at age 11 and drug use at ages 15 and 18 from self reports and assessed psychiatric symptoms at age 26 with a standardised interview schedule to obtain DSM-IV (diagnostic and statistical manual . . . [Full text of this article]

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Rapid Responses:

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early days

david h yates
bmj.com, 22 Nov 2002 [Full text]

Getting the right information for the debate

Francis T. Reilly
bmj.com, 23 Nov 2002 [Full text]

Specificity argument is unconvincing

Adam Jacobs
bmj.com, 25 Nov 2002 [Full text]

Psychosis - reason or consequence of cannabis use?

Anna Gombosova
bmj.com, 25 Nov 2002 [Full text]

Temporal relation between cannabis use and early onset schizophrenia

Martin Holtmann, et al.
bmj.com, 17 Dec 2002 [Full text]

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