BMJ 2002;325:429 ( 24 August )

Filler

Research samples are hard to obtain these days

The first 150 words of the full text of this article appear below.

I was a clinical research fellow coming to the end of my three year research programme on the aetiology of hepatobiliary cancers. One of my final studies was to analyse bile, collected via endoscopic retrograde cholangiopancreatography, with magnetic resonance spectroscopy to look for differences between patients with cancer and those without.

The initial spectroscopy readings were promising, with various bizarre, never previously seen peaks proudly announcing themselves. My initial excitement that I was on the verge of discovering the cause of biliary cancer was soon cut short, however, on realising that these peaks were probably due to the contrast agent used during cholangiopancreatography. Time was running out---I had to submit my thesis within a few months and still had other lab work to complete. What I needed, and quickly, was a fresh, contrast-free bile sample. But from where?

I was pondering on how I could acquire such a sample . . . [Full text of this article]


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