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Rose questionnaire is not what it seems
| The first 150 words of the full text of this article appear below. |
EDITOR
Macleod et al's paper on stress and cardiovascular disease
tells us two things.1 Firstly, the Rose angina
questionnaire rather inconveniently does not just measure angina in the
sense understood by cardiologists.2 Instead it measures
chest pain as understood by everyone else.
Most cases of chest pain in the general population are not due to heart
disease, and even in middle aged Scottish men the prevalence of
coronary heart disease is low, so the positive predictive value of the
Rose questionnaire will be poor.3 The relation between
stress and chest pain that the questionnaire measures is only a
"bias" in as much as it does not fit into the view of cardiovascular epidemiologists. The effect is real (and has important clinical implications to cardiologists) in that the Rose questionnaire is a superb measure of anxiety in young people but will mislead those
who interpret its results too credulously.3 The
strengthening the evidence base
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