BMJ 2002;325:173-174 ( 27 July )

Editorials

Daily doses of multivitamin tablets

Regular consumption will probably do you no good, with a few exceptions

The first 150 words of the full text of this article appear below.

Some 20-30% of the population in developed countries take a daily vitamin supplement. Does it do them any good? Our current estimates of vitamin requirements are based on the amounts needed to prevent deficiency diseases; in most countries deficiency is no longer a major problem. The question is whether higher levels of intake provide health benefits. There are two ways to answer this question: to identify biomarkers of optimum nutritional status, rather than the absence of deficiency; or epidemiological studies to identify nutrients associated with a lower incidence of chronic diseases, followed by intervention studies. Neither approach has yet provided satisfactory answers, and a recent review finds little convincing evidence in favour of supplements.1

A number of promising suggestions for biomarkers exist, including metabolic markers of damage from radicals, immune responses, and damage to DNA. None is responsive to only a single nutrient, and all are affected by a plethora . . . [Full text of this article]


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Relevant Article

Role of multivitamins and mineral supplements in preventing infections in elderly people: systematic review and meta-analysis of randomised controlled trials
Alia El-Kadiki and Alexander J Sutton
BMJ 2005 330: 871. [Abstract] [Full Text] [PDF]

This article has been cited by other articles:

  • Greenwald, P., Anderson, D., Nelson, S. A, Taylor, P. R (2007). Clinical trials of vitamin and mineral supplements for cancer prevention. Am. J. Clin. Nutr. 85: 314S-317S [Abstract] [Full text]  
  • El-Kadiki, A., Sutton, A. J (2005). Role of multivitamins and mineral supplements in preventing infections in elderly people: systematic review and meta-analysis of randomised controlled trials. BMJ 330: 871- [Abstract] [Full text]  
  • Bashir, O., FitzGerald, A.J., Goodlad, R.A. (2004). Both suboptimal and elevated vitamin intake increase intestinal neoplasia and alter crypt fission in the ApcMin/+ mouse. Carcinogenesis 25: 1507-1515 [Abstract] [Full text]  

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