Insulin pumps are still debatable for type 1 diabetes

doi:10.1136/bmj.325.7354.46

BMJ 2002;325:46 ( 6 July )

Letters

Insulin pumps are still debatable for type 1 diabetes

The first 150 words of the full text of this article appear below.

EDITOR $---$ We have three comments about Pickup et al's meta-analysis comparing insulin infusion with injection, which may casta different light on their main conclusion.¹

Firstly, the results of the largest study in the meta-analysis, the so called Dusseldorf study, needs careful interpretation.The authors have estimated this study to show a positive resultfor continuous subcutaneous insulin infusion, with an advantagein percentage of glycated haemoglobin of 0.68%. This figure willbe an estimation made from a graph, as exact data are not givenin the original paper. This seems to be a correct interpretationof the six month data of this study, but the total duration ofthe study was two years. At 12, 18, and 24 months the "advantage"of continuous subcutaneous insulin infusion can be estimated tobe 0.35%, -0.1%, and -0.2%, respectively. Thus another interpretationof this one study, representing 918 months of the meta-analysis'stotal of 2522 patient . . . [Full text of this article]

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Glycaemic control with continuous subcutaneous insulin infusion compared with intensive insulin injections in patients with type 1 diabetes: meta-analysis of randomised controlled trials: John Pickup, Martin Mattock, and Sally Kerry
BMJ 2002 324: 705. [Abstract] [Full Text] [PDF]

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