Dengue: an escalating problem

doi:10.1136/bmj.324.7353.1563

BMJ 2002;324:1563-1566 ( 29 June )

Clinical review

Dengue: an escalating problem

Robert V Gibbons, medical epidemiologist, David W Vaughn, chief.

Department of Virus Diseases, Walter Reed Army Institute of Research, Silver Spring, MD 20910-7500, USA

Correspondence to: R V Gibbons robert.gibbons@na.amedd.army.mil

The first 150 words of the full text of this article appear below.

Dengue viruses, single stranded RNA viruses of the family Flaviviridae, are the most common cause of arboviral disease inthe world. They are found virtually throughout the tropics (fig1) and cause an estimated 50-100 million illnesses annually, including250 000-500 000 cases of dengue haemorrhagic fever $---$ a severe manifestationof dengue $---$ and 24 000 deaths.^1-3 More than two fifths of the world'spopulation (2.5 billion) live in areas potentially at risk fordengue.¹ Because travellers to endemic areas are also at risk,healthcare providers should have an understanding of the spectrumof infection, how to diagnose it, and what the appropriate treatmentis.

Come then, let us play at unawares

And see who wins in this sly game of bluff

Man or mosquito

D H Lawrence, The Mosquito

Table Removed (Available Only in the Full Text)

	Methods

Our review was prepared from literature on dengue up to 15 April 2002. We searched Medline (for all English articles usingthe keyword "dengue"), comprehensive textbooks, the . . . [Full text of this article]

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