BMJ 2002;324:611 ( 9 March )

Letters

Secondary prevention of coronary heart disease

    Ill defined inclusion criteria resulted in missed trials
    Secondary prevention programmes may reduce overall mortality in high risk patients
    Improved outcomes need to be defined

Ill defined inclusion criteria resulted in missed trials

The first 150 words of the full text of this article appear below.

EDITOR---The review by McAlister et al of secondary prevention programmes in coronary heart disease does not adhere to some of the major principals of good practice when conducting systematic reviews of the medical literature.1-3 These include a clearly defined research question, strict inclusion criteria so that the review can be replicated, an exhaustive search of the medical literature to find all relevant studies, and findings that can be interpreted easily by the reader and relate to clinical practice.

McAlister et al, at first glance, have chosen a huge area of the medical literature to review, encompassing both pharmacological and non-pharmacological interventions for the secondary prevention of coronary heart disease. On closer inspection, they say that it is their intention to review the literature concerned with disease management programmes for coronary heart disease. The definition of disease management programmes used is broad and is quoted as that proposed by . . . [Full text of this article]


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Relevant Article

Randomised trials of secondary prevention programmes in coronary heart disease: systematic review
Finlay A McAlister, Fiona M E Lawson, Koon K Teo, and Paul W Armstrong
BMJ 2001 323: 957-962. [Abstract] [Full Text] [PDF]




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