BMJ 2002;324:26-27 ( 5 January )

Papers

Smoking during pregnancy and diabetes mellitus in a British longitudinal birth cohort

Scott M Montgomery, principal research fellowAnders Ekbom, professor

Enheten för Klinisk Epidemiologi, Karolinska Sjukhuset L1:00, SE-171 76, Stockholm, Sweden

Correspondence to: Dr Montgomery Scott.Montgomery@medks.ki.se

The first 150 words of the full text of this article appear below.

Exposures in utero may increase the risk of type 2 diabetes. 1 2 We tested the hypothesis that maternal smoking during pregnancy increases both the risk of early onset type 2 diabetes3 and non-diabetic obesity in offspring.


    Methods and results

We used data are from the British National Child Development Study (NCDS),4 based on the Perinatal Mortality Survey (PMS) of about 17 000 births from 3 to 9 March 1958. The first sweep of the study in 1965 had 15 396 responses. The cohort remained generally representative at age 33 years (n=11 359).5 Missing data reduced the proportion in social class V from 6.4% in sweep 1 to 5.3%. Ethics committee approval was obtained for research involving medical examinations, and cohort members signed consent forms at age 33 years allowing access to medical records.

Medical examinations and record reviews by local authority medical officers were conducted at ages 7 and 16 years. Children with incomplete or equivocal information on diabetes or with a recorded onset before the age of . . . [Full text of this article]


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Rapid Responses:

Read all Rapid Responses

Smoking Out Feeding's Impact
Linda F. Palmer
bmj.com, 5 Jan 2002 [Full text]
Re: Smoking Out Feeding's Impact
Scott M Montgomery
bmj.com, 11 Jan 2002 [Full text]



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