BMJ 2001;323:285 ( 4 August )

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Beware of cytogenetic results after successful bone marrow transplantation

The first 150 words of the full text of this article appear below.

EDITOR---Bone marrow transplantation is used in several haematological diseases, such as acute and chronic leukaemia, aplastic anaemia, and severe congenital immunodeficiencies.1 The survival rate has improved greatly over the past decade.2 Patients who have had successful bone marrow transplantation have peripheral blood cells originating from the donated bone marrow, and results of cytogenetic studies of these blood cells will relate to the donor. This is an important point to note if confusion is to be avoided, as was the case with two patients who presented to our centre.

Two male patients attended our unit with their spouses for infertility treatment. The cause of infertility in both cases was intensive radiotherapy and chemotherapy before allograft bone marrow transplantation. One patient (case 1) was 28 years old and the other (case 2) 31 years old. Acute lymphoplastic leukaemia had been diagnosed in both in 1998. The treatment of choice in both cases is . . . [Full text of this article]
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