A better oral rehydration solution?

doi:10.1136/bmj.323.7304.59

BMJ 2001;323:59-60 ( 14 July )

Editorials

A better oral rehydration solution?

An important step, but not a leap forward

Papers p 81

The first 150 words of the full text of this article appear below.

Diarrhoea remains one of the leading causes of death in children below 5 years of age in developing countries, resulting inover 4 million deaths a year. Most diarrhoeal deaths are causedby dehydration, which can be treated by replacing fluid loss withoral rehydration solution in over 90% of cases. For over 20 yearsthe World Health Organization and Unicef have recommended an oralrehydration solution containing 90 mmol/l of sodium and 111 mmol/lof glucose. ¹ ² This solution is of established efficacy intreating children and adults with diarrhoea regardless of itscause. Despite proved efficacy, the acceptance of oral rehydrationsolution by patients worldwide and particularly outside facility-basedtreatment centres has been less than optimal and even poor. Asa result, other formulations have been developed and tested, andthis week's issue carries a meta-analysis of studies comparingthe standard WHO oral rehydration solution with reduced osmolaritysolutions (p 81).³

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