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Inappropriate selection of cases and controls biased study
| The first 150 words of the full text of this article appear below. |
EDITOR
In their case-control study, Churchill et al found that
teenagers who become pregnant have higher consultation rates at general
practices than their age matched peers.1 However, their
conclusions may be biased by inappropriate selection of cases and controls.
Churchill et al defined cases as all registered patients in the practices who had a recorded termination, delivery, or miscarriage resulting from conception. Since they ascertained cases from practice computer records, maternity books, and knowledge of practice staff, the cases included only patients who received such services locally and not from other districts. Controls were, however, selected from the ordered list for the practice closest in chronological age as the cases. Hence the control group included registered patients who were actually resident in other districts. The inclusion of such patients would seriously underestimate the consultation rates in the control group.
The median age of the subjects was 17 years. A significant