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EDITOR
Campbell et al's study on prescribing indicators for general
practices in the United Kingdom showed how difficult it is to conduct
quality assurance of prescribing by using the existing prescription
pricing databases in the United Kingdom.1 The authors
selected 41 proxies of rational prescribing from prescribing analysis
and cost (PACT) data, the English system. Only seven of these were
rated as valid for economic rationality (cost) and five for scientific
rationality (quality).
This shows the impossibility of assessing prescribing rationality without knowing the diagnosis or patient identification. None of the prescription pricing databases in the United Kingdom records either of these. Yet from 1987 the American equivalent of the NHS, Medicaid, has used its database containing these data to screen monthly for two things: incompatible prescribing and inappropriate prescribing.2
Incompatible prescribing is the concurrent use of two or more drugs
that have serious interactions (a common cause of the 5%