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EDITOR
In the cluster of letters on the national service
framework for coronary heart disease,1 two letters (by
Lloyd-Mostyn and Cracknell) raise concerns about the recommendation to
reduce cholesterol concentration by 30%.2 I wish to
clarify the Department of Health's position. The wording of the advice
on cholesterol lowering in the national service framework was intended
to read: "Statin therapy should aim to lower cholesterol below 5.0 mmol/l or to reduce total serum cholesterol by 20-25%, whichever would result in the lowest level. Equivalent figures for LDL [low density lipoprotein] cholesterol would be 3.0 mmol/l or by 30% reduction, whichever results in the lowest level." This is consistent with the
joint British recommendations.3
On the matter of when to start statin treatment after acute myocardial
infarction, the joint British recommendations state: "Patients
admitted with unstable angina or acute MI [myocardial infarction]
. . . should . . . be prescribed lipid
lowering therapy before discharge."3 It was
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