BMJ 2000;321:781-782 ( 30 September )

Editorials

Testicular cancer and infertility

Abnormal semen analysis is associated with a small increase in risk

Paper p 789

The first 150 words of the full text of this article appear below.

The potential links between the detrimental environmental effects on reproduction and the worldwide increase in testicular cancer evoke huge interest in clinicians, scientists, and the public.1-3 The retrospective study by Jacobsen and colleagues in this issue (p 789) shows that men with abnormal semen analyses are at an increased risk of testicular cancer.4 These results provide more substantial evidence to support earlier studies reporting an increased incidence of testicular cancer in men who have few children for their age.5 The results show a higher risk in men with lower sperm counts, especially when combined with abnormal motility and abnormal sperm morphology, all of which suggest a more serious testicular defect.

The observation that the highest risk is found within the first two years after the semen analysis may be related to the early age at which the peak incidence of testicular cancer occurs.4 Most studies indicate that most testicular . . . [Full text of this article]
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Relevant Article

Risk of testicular cancer in men with abnormal semen characteristics: cohort study
Rune Jacobsen, Erik Bostofte, Gerda Engholm, Johnni Hansen, Jørgen H Olsen, Niels E Skakkebæk, and Henrik Møller
BMJ 2000 321: 789-792. [Abstract] [Full Text] [PDF]

This article has been cited by other articles:

  • Gleason, A. M. (2006). Racial Disparities in Testicular Cancer: Impact on Health Promotion. J Transcult Nurs 17: 58-64 [Abstract]  
  • Bahadur, G., Ozturk, O., Muneer, A., Wafa, R., Ashraf, A., Jaman, N., Patel, S., Oyede, A.W., Ralph, D.J. (2005). Semen quality before and after gonadotoxic treatment. Hum Reprod 20: 774-781 [Abstract] [Full text]  
  • Gandini, L., Lombardo, F., Salacone, P., Paoli, D., Anselmo, A. P., Culasso, F., Dondero, F., Lenzi, A. (2003). Testicular cancer and Hodgkin's disease: evaluation of semen quality. Hum Reprod 18: 796-801 [Abstract] [Full text]  
  • (2000). Semen Quality and Testicular Cancer. JWatch General 2000: 8-8 [Full text]  
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