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If early treatment fails, patients should be referred to pain clinics
| The first 150 words of the full text of this article appear below. |
Shingles, or herpes zoster, may occur at any stage in a person's life. Herpes zoster is the clinical manifestation of the reactivation of a lifelong latent infection with varicella zoster virus, usually contracted after an episode of chickenpox in early life.1 Varicella zoster virus tends to be reactivated only once in a lifetime, with the incidence of second attacks being <5%.2 Herpes zoster occurs more commonly in later life (as T cell immunity to the virus wanes) and in patients who have T cell immunosuppression.
Pain persisting after herpes zoster, termed post-herpetic neuralgia, is
the commonest and most feared complication. Its definition is
controversial, ranging from pain persisting after the rash heals to
pain persisting 30 days or 6 months after the onset of herpes zoster.
Some experts consider all pain during and after herpes zoster as a
continuum. Therefore we have suggested that this total duration of pain
and pain at
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