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Survival rates improve only in patients with the worst heart failure
| The first 150 words of the full text of this article appear below. |
In the early years after the introduction of heart transplantation the supply of donor hearts increased yearly as greater numbers of transplant centres came into existence and more patients with end stage heart disease were listed as transplant candidates. This parallel expansion of both donor and recipient numbers ceased around 1990, and since then the number of cardiac donors has plateaued at about 3500 a year worldwide while the number of patients listed to receive a heart transplant increases annually. 1 2 This increase in the number of patients waiting for a heart transplant has occurred despite major improvements in medical treatment for heart failure that have been introduced during this time.
This probably reflects the fact that most of the advances in the
treatment of heart failure have been essentially palliative. It may
also reflect a belief in the medical community that heart transplantation improves the chances of survival for patients who reach