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EDITOR
The new Sheffield table and its alternatives make little use of
a cardinal risk factor that is easy to assess.1 A family
history of coronary artery disease, especially when premature, is a
powerful and independent indicator of a person's risk. Failure to
include this element will cause these tables to underestimate the 10 year risk of cardiovascular disease and cannot be corrected for by
simply adding six years to the patient's age, as suggested in the
Sheffield table. The increase in risk depends on the exact details of
the family history and the patient's age and sex.
The GISSI-EFRIM investigators (Gruppo Italiano per lo Studio
della Sopravvivenza nell'Infarto-Epidemiologia dei Fattori di Rischio
dell'Infarto Miocardico) showed that a family history of myocardial
infarction is an independent risk factor for myocardial infarction,
with the number of relatives and the age at which they were affected
influencing the strength of the association.2
Israeli students are refusing to perform intimate examinations on anaesthetised women without their informed consent.