BMJ 2000;321:448 ( 12 August )

Letters

Family history is important in estimating coronary risk

The first 150 words of the full text of this article appear below.

EDITOR---The new Sheffield table and its alternatives make little use of a cardinal risk factor that is easy to assess.1 A family history of coronary artery disease, especially when premature, is a powerful and independent indicator of a person's risk. Failure to include this element will cause these tables to underestimate the 10 year risk of cardiovascular disease and cannot be corrected for by simply adding six years to the patient's age, as suggested in the Sheffield table. The increase in risk depends on the exact details of the family history and the patient's age and sex.

The GISSI-EFRIM investigators (Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto-Epidemiologia dei Fattori di Rischio dell'Infarto Miocardico) showed that a family history of myocardial infarction is an independent risk factor for myocardial infarction, with the number of relatives and the age at which they were affected influencing the strength of the association.2 . . . [Full text of this article]


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Related Article

Coronary and cardiovascular risk estimation for primary prevention: validation of a new Sheffield table in the 1995 Scottish health survey population
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BMJ 2000 320: 671-676. [Abstract] [Full Text] [PDF]

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