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Registering clinical trials
Register of clinical trials in children must be set upItalian clinical trial registry is kept by pharmacists on local
ethical committeesRegister of clinical trials in children must be set up
| The first 150 words of the full text of this article appear below. |
EDITOR
Tonks's paper1 and other efforts to boost
registration of new clinical trials2 should be supported.
Registration of clinical trials would benefit evidence based health
care and freedom of information and, more importantly, would benefit
patients, particularly children.
Randomised controlled trials aimed at meeting the requirements of
regulatory agencies are seldom carried out in paediatric patients, and
many children thus receive drugs that do not have labelling for
paediatric use.3 Furthermore, there is an imbalance in the
distribution of efforts and resources. Systematic studies (and reviews)
have focused mainly on a few childhood illnesses such as asthma, otitis
media, and respiratory tract infectionsas found by consulting the
Cochrane Library.
This longstanding, underprivileged position of children underlines the
need for further approaches aimed at promoting the rational use of
drugs in paediatric patients. Over the past 20 years the number and
diversity of databases available to the biomedical research
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